Assay Report Card

Basic Information

ID: ALA4008601

Type: Binding

Description: Chaperone activity assessed as enhancement of GCase N370S/84GG mutant enzyme in fibroblasts derived from type 1 gaucher disease patient at 20 uM treated for 5 days prior to addition of 4-methylumbelliferyl beta-D-glucopyranoside as substrate in presence of beta-cyclodextrin by luminescence spectrophotometry relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
665.472.402.40