Basic Information
ID: ALA4008609
Type: Binding
Description: Inhibition of recombinant human DHFR assessed as reduction in conversion of DHF to THF measured every 30 secs for 6 mins by UV-Vis spectrophotometric method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4008609
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 208.26 | 3.58 | 3.58 |
| 454.45 | 0.27 | 0.27 |
| 353.85 | 1.60 | 1.60 |
| 471.99 | 3.35 | 3.35 |
| 457.96 | 2.96 | 2.96 |
| 484.00 | 3.50 | 3.50 |
| 457.96 | 2.96 | 2.96 |
| 443.94 | 2.57 | 2.57 |
| 457.96 | 2.96 | 2.96 |
| 443.94 | 2.57 | 2.57 |
| 327.82 | 1.07 | 1.07 |
| 471.99 | 3.35 | 3.35 |
| 469.97 | 3.11 | 3.11 |
| 498.03 | 3.89 | 3.89 |
| 443.94 | 2.57 | 2.57 |
| 457.96 | 2.96 | 2.96 |
| 471.99 | 3.35 | 3.35 |
| 459.98 | 2.88 | 2.88 |
| 471.99 | 3.35 | 3.35 |
| 443.94 | 2.57 | 2.57 |