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Inhibition of recombinant human DHFR assessed as reduction in conversion of DHF to THF measured every 30 secs for 6 mins by UV-Vis spectrophotometric ...

Basic Information

ID: ALA4008609

Type: Binding

Description: Inhibition of recombinant human DHFR assessed as reduction in conversion of DHF to THF measured every 30 secs for 6 mins by UV-Vis spectrophotometric method

Format: BAO_0000357

Organism: Homo sapiens

Target:  Dihydrofolate reductase(ALA202)

Document:  ALA4007411

Inhibition of recombinant human DHFR assessed as reduction in conversion of DHF to THF measured every 30 secs for 6 mins by UV-Vis spectrophotometric method: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4008609

IC50

Total(20)

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
208.263.583.58
454.450.270.27
353.851.601.60
471.993.353.35
457.962.962.96
484.003.503.50
457.962.962.96
443.942.572.57
457.962.962.96
443.942.572.57
327.821.071.07
471.993.353.35
469.973.113.11
498.033.893.89
443.942.572.57
457.962.962.96
471.993.353.35
459.982.882.88
471.993.353.35
443.942.572.57
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