Basic Information
ID: ALA4008741
Type: Functional
Description: Agonist activity at human dopamine D2 receptor-short expressed in CHO-K1 cells assessed as reduction in adenylyl cyclase activator NKH 477 induced cAMP accumulation preincubated for 10 mins followed by NKH 477 addition by HTRF assay relative to dopamine
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4008741
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 539.46 | 5.23 | 5.23 |
| 559.47 | 5.59 | 5.59 |
| 527.45 | 5.06 | 5.06 |
| 472.59 | 5.02 | 5.02 |
| 541.48 | 5.45 | 5.45 |
| 488.59 | 3.76 | 3.76 |
| 534.92 | 6.35 | 6.35 |
| 488.59 | 3.76 | 3.76 |
| 557.45 | 5.37 | 5.37 |
| 527.45 | 5.06 | 5.06 |
| 541.48 | 5.45 | 5.45 |
| 486.62 | 4.45 | 4.45 |
| 539.08 | 4.15 | 4.15 |
| 502.62 | 4.15 | 4.15 |
| 532.64 | 4.16 | 4.16 |
| 484.43 | 5.96 | 5.96 |