Basic Information
ID: ALA4008766
Type: Binding
Description: Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using biotinylated H3K4me1 peptide as substrate preincubated for 20 mins measured after 1 hr by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4008766
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 256.33 | 3.49 | 3.49 |
| 230.35 | 2.40 | 2.40 |
| 266.39 | ||
| 299.40 | 3.56 | 3.56 |
| 253.31 | 2.77 | 2.77 |
| 378.45 | 4.78 | 4.78 |
| 318.40 | 4.94 | 4.94 |
| 349.42 | 4.68 | 4.68 |
| 508.12 | 4.70 | 4.70 |
| 257.32 | 2.89 | 2.89 |
| 257.32 | 2.89 | 2.89 |
| 313.43 | 3.55 | 3.55 |
| 285.37 | 2.91 | 2.91 |
| 300.38 | 3.64 | 3.64 |
| 284.38 | 4.11 | 4.11 |
| 257.32 | 2.89 | 2.89 |
| 270.36 | 3.80 | 3.80 |
| 335.23 | 4.25 | 4.25 |
| 363.44 | 4.47 | 4.47 |
| 258.31 | 2.28 | 2.28 |
| 284.38 | 4.37 | 4.37 |
| 253.33 | 4.15 | 4.15 |
| 316.45 | 4.36 | 4.36 |
| 259.36 | 4.22 | 4.22 |
| 355.46 | 3.32 | 3.32 |
| 286.36 | 2.98 | 2.98 |
| 354.48 | 3.24 | 3.24 |
| 240.27 | 2.15 | 2.15 |
| 286.36 | 3.50 | 3.50 |
| 257.32 | 2.89 | 2.89 |
| 242.30 | 3.48 | 3.48 |
| 461.59 | 5.20 | 5.20 |
| 300.38 | 3.64 | 3.64 |
| 363.44 | 4.47 | 4.47 |
| 335.23 | 4.25 | 4.25 |
| 272.39 | 2.46 | 2.46 |
| 257.32 | 2.89 | 2.89 |
| 382.23 | 4.10 | 4.10 |
| 313.43 | 3.55 | 3.55 |
| 274.32 | 3.63 | 3.63 |
| 270.36 | 3.80 | 3.80 |
| 299.36 | 2.59 | 2.59 |
| 475.61 | 5.54 | 5.54 |
| 274.32 | 3.63 | 3.63 |
| 257.32 | 2.89 | 2.89 |
| 256.33 | 3.49 | 3.49 |
| 313.43 | 3.55 | 3.55 |
| 240.26 | 3.02 | 3.02 |
| 290.78 | 4.15 | 4.15 |
| 382.47 | 4.19 | 4.19 |
| 254.29 | 2.16 | 2.16 |
| 383.52 | 4.21 | 4.21 |
| 258.31 | 2.28 | 2.28 |
| 362.45 | 5.07 | 5.07 |
| 270.36 | 3.98 | 3.98 |
| 290.77 | 4.15 | 4.15 |
| 254.29 | 2.16 | 2.16 |
| 270.36 | 3.80 | 3.80 |
| 382.23 | 4.10 | 4.10 |