Basic Information
ID: ALA4008777
Type: Binding
Description: Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli at 10 uM using biotinylated H3K4me1 peptide as substrate preincubated for 10 mins with enzyme followed by substrate addition measured after 1 hr by TR-FRET HTS assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4008777
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 314.37 | 3.28 | 3.28 |
| 256.33 | 3.49 | 3.49 |
| 298.30 | 2.81 | 2.81 |
| 282.30 | 3.23 | 3.23 |
| 300.38 | 3.64 | 3.64 |
| 284.31 | 3.17 | 3.17 |
| 270.29 | 3.03 | 3.03 |
| 270.36 | 3.52 | 3.52 |
| 316.45 | 4.36 | 4.36 |
| 270.29 | 3.03 | 3.03 |
| 274.32 | 3.63 | 3.63 |
| 286.36 | 3.50 | 3.50 |
| 298.30 | 2.81 | 2.81 |
| 258.25 | 3.16 | 3.16 |
| 274.32 | 3.63 | 3.63 |
| 290.77 | 4.15 | 4.15 |
| 240.26 | 3.02 | 3.02 |
| 288.73 | 3.70 | 3.70 |
| 300.38 | 3.89 | 3.89 |
| 286.36 | 3.50 | 3.50 |
| 290.77 | 4.15 | 4.15 |
| 254.29 | 3.05 | 3.05 |
| 298.37 | 3.69 | 3.69 |