Basic Information
ID: ALA4008790
Type: Binding
Description: Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as substrate incubated for 20 mins measured after 1 hr by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4008790
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 256.33 | 3.49 | 3.49 |
| 230.35 | 2.40 | 2.40 |
| 489.64 | 5.93 | 5.93 |
| 519.67 | 5.74 | 5.74 |
| 475.61 | 5.54 | 5.54 |
| 487.63 | 5.73 | 5.73 |
| 447.56 | 4.81 | 4.81 |
| 363.44 | 4.47 | 4.47 |
| 300.38 | 3.64 | 3.64 |
| 475.61 | 5.54 | 5.54 |
| 461.59 | 5.20 | 5.20 |
| 519.67 | 5.69 | 5.69 |
| 363.44 | 4.47 | 4.47 |
| 475.61 | 5.54 | 5.54 |
| 460.60 | 5.24 | 5.24 |
| 433.54 | 4.05 | 4.05 |
| 363.44 | 4.47 | 4.47 |
| 505.64 | 5.21 | 5.21 |
| 505.64 | 5.35 | 5.35 |
| 461.59 | 5.06 | 5.06 |
| 466.65 | 4.58 | 4.58 |
| 363.44 | 4.47 | 4.47 |
| 519.67 | 5.74 | 5.74 |
| 475.61 | 5.54 | 5.54 |
| 461.59 | 5.06 | 5.06 |
| 461.59 | 5.20 | 5.20 |
| 459.62 | 6.06 | 6.06 |
| 286.36 | 3.50 | 3.50 |
| 560.72 | 5.03 | 5.03 |
| 461.59 | 5.20 | 5.20 |
| 475.61 | 5.72 | 5.72 |
| 363.44 | 4.47 | 4.47 |
| 445.59 | 5.22 | 5.22 |
| 300.38 | 3.64 | 3.64 |
| 363.44 | 4.47 | 4.47 |
| 475.61 | 5.54 | 5.54 |
| 447.56 | 4.67 | 4.67 |
| 519.67 | 5.60 | 5.60 |
| 449.58 | 5.06 | 5.06 |
| 300.38 | 3.64 | 3.64 |
| 475.61 | 5.45 | 5.45 |
| 474.59 | 4.88 | 4.88 |
| 286.36 | 3.50 | 3.50 |
| 503.62 | 5.46 | 5.46 |
| 459.62 | 5.41 | 5.41 |
| 505.64 | 5.21 | 5.21 |
| 551.71 | 7.11 | 7.11 |
| 533.69 | 6.13 | 6.13 |
| 474.63 | 4.82 | 4.82 |
| 286.36 | 3.50 | 3.50 |
| 475.61 | 5.59 | 5.59 |
| 446.58 | 4.48 | 4.48 |
| 475.61 | 5.54 | 5.54 |