Assay Report Card

Basic Information

ID: ALA4009222

Type: Functional

Description: Antiinflammatory activity in oxazolone-induced delayed type hypersensitivity BALB/c mouse model assessed as effect on histology changes at 0.1 to 2.5 mg applied topically on ear administered 3 hrs prior to oxazolone challenge on day 7 to 12 post sensitization followed by re-administration of compound on day 13 to 18 without oxazolone challenge measured daily prior to treatment from day 7 to 19 by H and E staining based assay

Organism: Mus musculus

Strain: BALB/c

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
437.491.771.77
455.933.273.27
490.452.002.00
453.942.292.29
435.952.152.15