Basic Information
ID: ALA4009226
Type: ADME
Description: Inhibition of recombinant human LTA4H aminopeptidase activity expressed in Escherichia coli BL21 (DE3) pLysS assessed as formation of p-NA from Ala-p-NA preincubated for 10 mins followed by substrate addition measured after 10 mins
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4009226
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 166.20 | 2.29 | 2.29 |
| 264.32 | 2.47 | 2.47 |
| 302.37 | 2.58 | 2.58 |
| 376.42 | 3.34 | 3.34 |
| 326.35 | 2.50 | 2.50 |
| 307.39 | 1.94 | 1.94 |
| 721.88 | 8.62 | 8.62 |
| 396.45 | 3.99 | 3.99 |
| 318.35 | 2.01 | 2.01 |
| 349.43 | 3.33 | 3.33 |
| 434.50 | 4.20 | 4.20 |
| 421.50 | 4.55 | 4.55 |
| 358.49 | 3.24 | 3.24 |
| 397.43 | 2.42 | 2.42 |
| 394.48 | 2.09 | 2.09 |
| 433.51 | 4.13 | 4.13 |
| 339.44 | 3.51 | 3.51 |
| 349.41 | 1.31 | 1.31 |