Basic Information
ID: ALA4009341
Type: Binding
Description: Inhibition of full length recombinant human ALDH1A3 expressed in Escherichia coli BL21(DE3) assessed as reduction in dehydrogenase activity by measuring NAD(P)H level preincubated for 2 mins followed by addition of propionaldehyde as substrate in presence of NAD+ by spectrophotometric method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4009341
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 231.29 | 2.95 | 2.95 |
| 416.38 | 0.34 | 0.34 |
| 367.45 | 4.41 | 4.41 |
| 254.28 | 3.64 | 3.64 |
| 262.26 | 2.04 | 2.04 |
| 256.30 | 4.11 | 4.11 |
| 242.27 | 3.77 | 3.77 |
| 344.39 | 3.03 | 3.03 |
| 268.31 | 4.03 | 4.03 |
| 270.33 | 4.42 | 4.42 |