Inhibition of DNA synthesis in human CCRF-CEM cells assessed as decrease in BrdU incorporation by measuring synthesized DNA levels at 5 times IC50 aft...

Basic Information

ID: ALA4009397

Type: Functional

Description: Inhibition of DNA synthesis in human CCRF-CEM cells assessed as decrease in BrdU incorporation by measuring synthesized DNA levels at 5 times IC50 after 24 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 52.66%)

Format: BAO_0000219

Organism: Homo sapiens

Cell type: CCRF-CEM

Target:  CCRF-CEM(ALA382)

Document:  ALA4007430

Inhibition of DNA synthesis in human CCRF-CEM cells assessed as decrease in BrdU incorporation by measuring synthesized DNA levels at 5 times IC50 after 24 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 52.66%): 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
321.360.570.57
337.360.270.27
353.430.980.98
337.360.270.27
353.430.980.98
321.360.570.57