Drug metabolism in human HCT116 cells assessed as ADK-mediated 4-(Methylsulfanyl)-8-(beta-D-ribofuranosyl)-8H-thieno[2, 3:4,5]-pyrrolo[2,3-d]pyrimidin...

Basic Information

ID: ALA4009405

Type: ADME

Description: Drug metabolism in human HCT116 cells assessed as ADK-mediated 4-(Methylsulfanyl)-8-(beta-D-ribofuranosyl)-8H-thieno[2, 3:4,5]-pyrrolo[2,3-d]pyrimidine-5-O-monophosphate Sodium Salt formation per 5 x10'5 cells at 1 umol/L after 3 hrs by UPLC-MS/MS analysis

Format: BAO_0000219

Organism: Homo sapiens

Target:  Adenosine kinase(ALA3589)

Document:  ALA4007430

Drug metabolism in human HCT116 cells assessed as ADK-mediated 4-(Methylsulfanyl)-8-(beta-D-ribofuranosyl)-8H-thieno[2, 3:4,5]-pyrrolo[2,3-d]pyrimidine-5-O-monophosphate Sodium Salt formation per 5 x10'5 cells at 1 umol/L after 3 hrs by UPLC-MS/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
455.391.101.10