Basic Information
ID: ALA4010348
Type: Functional
Description: Sensitization of TRAIL-induced apoptosis in human ACHN cells assessed as reduction in cell viability preincubated for 2 hrs followed by addition of TRAIL measured after 18 hrs by MTS assay
Organism: Homo sapiens
Cell type: ACHN
Activity Charts
Bioactivity
Activity Types for Assay ALA4010348
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.61 | 3.35 | 3.35 |
| 502.60 | 1.73 | 1.73 |
| 486.61 | 2.75 | 2.75 |
| 554.68 | 4.49 | 4.49 |
| 602.68 | 1.60 | 1.60 |
| 586.68 | 2.63 | 2.63 |
| 528.64 | 3.09 | 3.09 |
| 544.64 | 2.30 | 2.30 |
| 544.64 | 2.30 | 2.30 |
| 544.64 | 2.06 | 2.06 |
| 702.75 | 1.71 | 1.71 |
| 545.63 | 2.24 | 2.24 |
| 504.62 | 1.95 | 1.95 |
| 602.68 | 1.84 | 1.84 |
| 764.82 | -0.58 | -0.58 |
| 502.60 | 1.73 | 1.73 |
| 544.64 | 2.30 | 2.30 |
| 612.72 | 2.57 | 2.57 |
| 602.68 | 1.84 | 1.84 |
| 560.64 | 1.51 | 1.51 |
| 626.72 | 2.11 | 2.11 |
| 502.60 | 1.73 | 1.73 |
| 546.66 | 2.52 | 2.52 |
| 602.68 | 1.60 | 1.60 |
| 576.68 | 2.15 | 2.15 |
| 544.64 | 2.30 | 2.30 |
| 560.64 | 2.52 | 2.52 |
| 644.71 | 2.17 | 2.17 |
| 484.59 | 2.72 | 2.72 |
| 684.76 | 1.65 | 1.65 |
| 587.67 | 2.81 | 2.81 |
| 560.64 | 1.27 | 1.27 |
| 500.59 | 1.93 | 1.93 |
| 486.61 | 2.51 | 2.51 |
| 560.64 | 1.27 | 1.27 |
| 764.82 | -0.58 | -0.58 |
| 596.68 | 2.61 | 2.61 |