Basic Information
ID: ALA4010769
Type: Binding
Description: Inhibition of recombinant human TACE catalytic domain using Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH2 as substrate after 2 hrs by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4010769
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 414.51 | 0.45 | 0.45 |
| 497.62 | 4.05 | 4.05 |
| 514.65 | 2.58 | 2.58 |
| 538.65 | 0.99 | 0.99 |
| 502.64 | 2.49 | 2.49 |
| 455.54 | 3.03 | 3.03 |
| 455.54 | 3.03 | 3.03 |
| 471.54 | 2.41 | 2.41 |
| 530.65 | 2.21 | 2.21 |
| 487.58 | 2.12 | 2.12 |
| 528.63 | 1.96 | 1.96 |
| 380.42 | 0.36 | 0.36 |
| 531.63 | 4.25 | 4.25 |
| 512.59 | 2.24 | 2.24 |
| 474.58 | 1.66 | 1.66 |
| 544.67 | 2.60 | 2.60 |
| 445.54 | 2.36 | 2.36 |
| 395.44 | -0.18 | -0.18 |
| 487.58 | 2.12 | 2.12 |
| 380.42 | 0.36 | 0.36 |
| 469.56 | 3.42 | 3.42 |
| 564.66 | 2.87 | 2.87 |
| 302.33 | 1.06 | 1.06 |
| 457.51 | 2.02 | 2.02 |
| 380.42 | 0.36 | 0.36 |
| 516.62 | 1.96 | 1.96 |
| 518.59 | 1.79 | 1.79 |
| 466.54 | 2.03 | 2.03 |
| 542.66 | 2.35 | 2.35 |
| 503.58 | 3.92 | 3.92 |
| 516.62 | 1.96 | 1.96 |
| 502.59 | 1.57 | 1.57 |
| 380.42 | 0.36 | 0.36 |
| 487.58 | 2.12 | 2.12 |
| 473.60 | 3.14 | 3.14 |
| 338.38 | 0.60 | 0.60 |
| 460.56 | 1.32 | 1.32 |
| 544.67 | 2.60 | 2.60 |
| 409.49 | 2.82 | 2.82 |
| 487.58 | 2.12 | 2.12 |