Basic Information
ID: ALA4010777
Type: Binding
Description: Inhibition of TACE in NHEK assessed as reduction in LPS/TPA-stimulated TNFalpha production preincubated for 1 hr followed by LPS/TPA stimulation for 24 hrs by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4010777
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 414.51 | 0.45 | 0.45 |
| 514.65 | 2.58 | 2.58 |
| 502.64 | 2.49 | 2.49 |
| 455.54 | 3.03 | 3.03 |
| 455.54 | 3.03 | 3.03 |
| 528.63 | 1.96 | 1.96 |
| 445.54 | 2.36 | 2.36 |
| 487.58 | 2.12 | 2.12 |
| 503.58 | 3.92 | 3.92 |
| 502.59 | 1.57 | 1.57 |
| 544.67 | 2.60 | 2.60 |