Basic Information
ID: ALA4010786
Type: Binding
Description: Inhibition of TACE in human PBMC assessed as inhibition of LPS-stimulated TNFalpha production
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4010786
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 390.42 | 3.02 | 3.02 |
| 428.34 | 4.20 | 4.20 |
| 519.62 | 3.62 | 3.62 |
| 311.41 | 2.05 | 2.05 |
| 413.42 | 4.13 | 4.13 |
| 533.65 | 4.01 | 4.01 |
| 401.53 | 3.92 | 3.92 |
| 388.49 | 2.91 | 2.91 |
| 554.69 | 2.61 | 2.61 |
| 505.59 | 3.23 | 3.23 |
| 461.58 | 3.94 | 3.94 |
| 422.58 | 3.60 | 3.60 |
| 390.42 | 3.02 | 3.02 |
| 491.57 | 2.84 | 2.84 |
| 419.50 | 2.91 | 2.91 |
| 475.61 | 4.33 | 4.33 |
| 447.56 | 3.55 | 3.55 |
| 447.56 | 3.69 | 3.69 |