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Antagonist activity at human P2Y4 receptor transfected in human 1321N1 cells assessed as inhibition of UTP-activated intracellular calcium mobilizatio...

Basic Information

ID: ALA4011248

Type: Functional

Description: Antagonist activity at human P2Y4 receptor transfected in human 1321N1 cells assessed as inhibition of UTP-activated intracellular calcium mobilization preincubated for 30 mins followed by UTP addition by fluo-4-dye based fluorescence assay

Format: BAO_0000219

Organism: Homo sapiens

Target:  Pyrimidinergic receptor P2Y4(ALA2123)

Document:  ALA4007497

Antagonist activity at human P2Y4 receptor transfected in human 1321N1 cells assessed as inhibition of UTP-activated intracellular calcium mobilization preincubated for 30 mins followed by UTP addition by fluo-4-dye based fluorescence assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
840.123.853.85
507.504.784.78
450.843.693.69
450.833.693.69
446.423.043.04
446.423.043.04
444.443.603.60
444.443.653.65
444.443.653.65
444.443.653.65
430.423.343.34
430.423.343.34
430.423.343.34
416.393.033.03
430.422.902.90
444.442.952.95
466.454.194.19
460.402.732.73
432.392.742.74
494.843.393.39
494.843.393.39
506.524.634.63
524.565.195.19
508.494.834.83
434.383.173.17
495.293.803.80
460.402.732.73
460.402.732.73
478.392.872.87
539.303.503.50
478.392.872.87
456.412.872.87
840.123.853.85
444.443.603.60
444.443.653.65
446.423.043.04
476.443.053.05
434.383.173.17
495.293.803.80
452.373.313.31
424.433.043.04
412.403.173.17
464.864.004.00
476.443.053.05
458.473.993.99
587.385.595.59
476.402.442.44
446.423.053.05
346.364.244.24
460.443.353.35
526.484.974.97
444.443.603.60
478.392.872.87
390.373.933.93
552.615.805.80
480.863.703.70
464.864.004.00
450.843.693.69
552.615.805.80
464.413.183.18
539.574.724.72
542.935.485.48
505.402.642.64
358.404.104.10
552.615.805.80