ID: ALA4011248
Type: Functional
Description: Antagonist activity at human P2Y4 receptor transfected in human 1321N1 cells assessed as inhibition of UTP-activated intracellular calcium mobilization preincubated for 30 mins followed by UTP addition by fluo-4-dye based fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Pyrimidinergic receptor P2Y4(ALA2123)
Document: ALA4007497
Antagonist activity at human P2Y4 receptor transfected in human 1321N1 cells assessed as inhibition of UTP-activated intracellular calcium mobilization preincubated for 30 mins followed by UTP addition by fluo-4-dye based fluorescence assay: 1
Bioactivity
Activity Types for Assay ALA4011248
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
840.12 | 3.85 | 3.85 |
507.50 | 4.78 | 4.78 |
450.84 | 3.69 | 3.69 |
450.83 | 3.69 | 3.69 |
446.42 | 3.04 | 3.04 |
446.42 | 3.04 | 3.04 |
444.44 | 3.60 | 3.60 |
444.44 | 3.65 | 3.65 |
444.44 | 3.65 | 3.65 |
444.44 | 3.65 | 3.65 |
430.42 | 3.34 | 3.34 |
430.42 | 3.34 | 3.34 |
430.42 | 3.34 | 3.34 |
416.39 | 3.03 | 3.03 |
430.42 | 2.90 | 2.90 |
444.44 | 2.95 | 2.95 |
466.45 | 4.19 | 4.19 |
460.40 | 2.73 | 2.73 |
432.39 | 2.74 | 2.74 |
494.84 | 3.39 | 3.39 |
494.84 | 3.39 | 3.39 |
506.52 | 4.63 | 4.63 |
524.56 | 5.19 | 5.19 |
508.49 | 4.83 | 4.83 |
434.38 | 3.17 | 3.17 |
495.29 | 3.80 | 3.80 |
460.40 | 2.73 | 2.73 |
460.40 | 2.73 | 2.73 |
478.39 | 2.87 | 2.87 |
539.30 | 3.50 | 3.50 |
478.39 | 2.87 | 2.87 |
456.41 | 2.87 | 2.87 |
840.12 | 3.85 | 3.85 |
444.44 | 3.60 | 3.60 |
444.44 | 3.65 | 3.65 |
446.42 | 3.04 | 3.04 |
476.44 | 3.05 | 3.05 |
434.38 | 3.17 | 3.17 |
495.29 | 3.80 | 3.80 |
452.37 | 3.31 | 3.31 |
424.43 | 3.04 | 3.04 |
412.40 | 3.17 | 3.17 |
464.86 | 4.00 | 4.00 |
476.44 | 3.05 | 3.05 |
458.47 | 3.99 | 3.99 |
587.38 | 5.59 | 5.59 |
476.40 | 2.44 | 2.44 |
446.42 | 3.05 | 3.05 |
346.36 | 4.24 | 4.24 |
460.44 | 3.35 | 3.35 |
526.48 | 4.97 | 4.97 |
444.44 | 3.60 | 3.60 |
478.39 | 2.87 | 2.87 |
390.37 | 3.93 | 3.93 |
552.61 | 5.80 | 5.80 |
480.86 | 3.70 | 3.70 |
464.86 | 4.00 | 4.00 |
450.84 | 3.69 | 3.69 |
552.61 | 5.80 | 5.80 |
464.41 | 3.18 | 3.18 |
539.57 | 4.72 | 4.72 |
542.93 | 5.48 | 5.48 |
505.40 | 2.64 | 2.64 |
358.40 | 4.10 | 4.10 |
552.61 | 5.80 | 5.80 |