Basic Information
ID: ALA4011248
Type: Functional
Description: Antagonist activity at human P2Y4 receptor transfected in human 1321N1 cells assessed as inhibition of UTP-activated intracellular calcium mobilization preincubated for 30 mins followed by UTP addition by fluo-4-dye based fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4011248
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 840.12 | 3.85 | 3.85 |
| 507.50 | 4.78 | 4.78 |
| 450.84 | 3.69 | 3.69 |
| 450.83 | 3.69 | 3.69 |
| 446.42 | 3.04 | 3.04 |
| 446.42 | 3.04 | 3.04 |
| 444.44 | 3.60 | 3.60 |
| 444.44 | 3.65 | 3.65 |
| 444.44 | 3.65 | 3.65 |
| 444.44 | 3.65 | 3.65 |
| 430.42 | 3.34 | 3.34 |
| 430.42 | 3.34 | 3.34 |
| 430.42 | 3.34 | 3.34 |
| 416.39 | 3.03 | 3.03 |
| 430.42 | 2.90 | 2.90 |
| 444.44 | 2.95 | 2.95 |
| 466.45 | 4.19 | 4.19 |
| 460.40 | 2.73 | 2.73 |
| 432.39 | 2.74 | 2.74 |
| 494.84 | 3.39 | 3.39 |
| 494.84 | 3.39 | 3.39 |
| 506.52 | 4.63 | 4.63 |
| 524.56 | 5.19 | 5.19 |
| 508.49 | 4.83 | 4.83 |
| 434.38 | 3.17 | 3.17 |
| 495.29 | 3.80 | 3.80 |
| 460.40 | 2.73 | 2.73 |
| 460.40 | 2.73 | 2.73 |
| 478.39 | 2.87 | 2.87 |
| 539.30 | 3.50 | 3.50 |
| 478.39 | 2.87 | 2.87 |
| 456.41 | 2.87 | 2.87 |
| 840.12 | 3.85 | 3.85 |
| 444.44 | 3.60 | 3.60 |
| 444.44 | 3.65 | 3.65 |
| 446.42 | 3.04 | 3.04 |
| 476.44 | 3.05 | 3.05 |
| 434.38 | 3.17 | 3.17 |
| 495.29 | 3.80 | 3.80 |
| 452.37 | 3.31 | 3.31 |
| 424.43 | 3.04 | 3.04 |
| 412.40 | 3.17 | 3.17 |
| 464.86 | 4.00 | 4.00 |
| 476.44 | 3.05 | 3.05 |
| 458.47 | 3.99 | 3.99 |
| 587.38 | 5.59 | 5.59 |
| 476.40 | 2.44 | 2.44 |
| 446.42 | 3.05 | 3.05 |
| 346.36 | 4.24 | 4.24 |
| 460.44 | 3.35 | 3.35 |
| 526.48 | 4.97 | 4.97 |
| 444.44 | 3.60 | 3.60 |
| 478.39 | 2.87 | 2.87 |
| 390.37 | 3.93 | 3.93 |
| 552.61 | 5.80 | 5.80 |
| 480.86 | 3.70 | 3.70 |
| 464.86 | 4.00 | 4.00 |
| 450.84 | 3.69 | 3.69 |
| 552.61 | 5.80 | 5.80 |
| 464.41 | 3.18 | 3.18 |
| 539.57 | 4.72 | 4.72 |
| 542.93 | 5.48 | 5.48 |
| 505.40 | 2.64 | 2.64 |
| 358.40 | 4.10 | 4.10 |
| 552.61 | 5.80 | 5.80 |