Basic Information
ID: ALA4011348
Type: Binding
Description: Inhibition of recombinant human SERT expressed in HEK293 cell membranes assessed as reduction in [3H]5-HT uptake incubated for 22 mins by micro beta scintillation counting analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4011348
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 284.75 | 2.61 | 2.61 |
| 303.36 | 1.87 | 1.87 |
| 454.44 | 0.57 | 0.57 |
| 458.93 | 1.01 | 1.01 |
| 503.38 | 1.12 | 1.12 |
| 486.99 | 1.79 | 1.79 |
| 383.25 | 3.03 | 3.03 |
| 459.92 | 1.44 | 1.44 |
| 504.37 | 1.55 | 1.55 |
| 457.94 | 1.62 | 1.62 |
| 449.88 | 0.77 | 0.77 |
| 473.94 | 1.83 | 1.83 |
| 487.97 | 2.22 | 2.22 |