Basic Information
ID: ALA4011359
Type: Binding
Description: Inhibition of [3H]mazindol binding to recombinant human SERT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4011359
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 284.75 | 2.61 | 2.61 |
| 303.36 | 1.87 | 1.87 |
| 471.97 | 2.01 | 2.01 |
| 383.25 | 3.03 | 3.03 |
| 459.92 | 1.44 | 1.44 |
| 550.04 | 3.05 | 3.05 |
| 502.00 | 2.61 | 2.61 |
| 504.37 | 1.55 | 1.55 |
| 457.94 | 1.62 | 1.62 |
| 487.97 | 2.22 | 2.22 |
| 445.89 | 1.35 | 1.35 |
| 472.95 | 2.43 | 2.43 |
| 516.02 | 2.85 | 2.85 |
| 487.97 | 0.34 | 0.34 |
| 476.95 | 1.13 | 1.13 |
| 448.89 | 0.35 | 0.35 |
| 449.88 | 0.77 | 0.77 |
| 473.94 | 1.83 | 1.83 |
| 564.07 | 3.44 | 3.44 |
| 518.39 | 1.94 | 1.94 |
| 487.97 | 2.22 | 2.22 |
| 556.09 | 3.78 | 3.78 |