Basic Information
ID: ALA4011522
Type: Binding
Description: Inhibition of full length GST-tagged PDE1B (unknown origin) assessed as decrease in FAM-cAMP hydrolysis preincubated for 5 mins followed by FAM-cAMP addition measured after 30 mins by IMAP assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4011522
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 501.63 | 5.76 | 5.76 |
| 350.46 | 4.15 | 4.15 |
| 370.87 | 3.69 | 3.69 |
| 483.57 | 3.09 | 3.09 |
| 385.88 | 2.80 | 2.80 |
| 435.55 | 2.94 | 2.94 |
| 439.93 | 3.10 | 3.10 |
| 487.99 | 3.73 | 3.73 |
| 427.92 | 2.56 | 2.56 |
| 425.95 | 3.58 | 3.58 |
| 470.00 | 3.59 | 3.59 |
| 471.49 | 2.70 | 2.70 |
| 501.56 | 3.50 | 3.50 |
| 461.98 | 4.37 | 4.37 |
| 465.58 | 2.95 | 2.95 |