Assay Report Card

Basic Information

ID: ALA4011564

Type: Binding

Description: Poison activity at recombinant Top1 (unknown origin) assessed as inhibition of [32P]-DNA religation in drug-DNA-Top1 ternary complex at 0.1 to 10 uM after 20 mins by PAGE analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
465.492.612.61