ID: ALA4011671
Type: ADME
Description: Inhibition of recombinant human BSEP expressed in baculovirus infected sf21 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-taurocholate uptake in to vesicles after 5 mins by microbeta filtration method
Organism: Homo sapiens
Subcellular Fraction: Plasma Membrane
Bioactivity
Activity Types for Assay ALA4011671
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
330.75 | 1.89 | 1.89 |
404.34 | 5.50 | 5.50 |
118.16 | -0.22 | -0.22 |
581.58 | -8.16 | -8.16 |
466.98 | 4.10 | 4.10 |