Assay Report Card

Basic Information

ID: ALA4011671

Type: ADME

Description: Inhibition of recombinant human BSEP expressed in baculovirus infected sf21 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-taurocholate uptake in to vesicles after 5 mins by microbeta filtration method

Organism: Homo sapiens

Subcellular Fraction: Plasma Membrane

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
330.751.891.89
404.345.505.50
118.16-0.22-0.22
581.58-8.16-8.16
466.984.104.10