Basic Information
ID: ALA4011674
Type: ADME
Description: Induction of mitochondrial dysfunction in Sprague-Dawley rat liver mitochondria assessed as inhibition of mitochondrial respiration per mg mitochondrial protein measured for 20 mins by A65N-1 oxygen probe based fluorescence assay
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Activity Charts
Bioactivity
Activity Types for Assay ALA4011674
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 303.29 | 1.77 | 1.77 |
| 441.55 | 4.37 | 4.37 |
| 430.38 | 2.88 | 2.88 |
| 407.51 | 4.95 | 4.95 |
| 330.75 | 1.89 | 1.89 |
| 385.51 | 2.09 | 2.09 |
| 494.01 | 3.64 | 3.64 |
| 853.92 | 3.74 | 3.74 |
| 404.55 | 4.20 | 4.20 |
| 314.47 | 4.72 | 4.72 |
| 344.85 | 5.38 | 5.38 |
| 300.44 | 5.60 | 5.60 |
| 581.07 | 6.14 | 6.14 |
| 670.86 | 3.09 | 3.09 |
| 613.80 | 2.87 | 2.87 |
| 567.80 | 4.75 | 4.75 |
| 505.64 | 2.40 | 2.40 |
| 356.45 | 3.16 | 3.16 |
| 357.44 | 2.49 | 2.49 |
| 281.36 | 2.84 | 2.84 |
| 575.69 | 5.70 | 5.70 |
| 371.87 | 2.36 | 2.36 |
| 470.02 | 3.55 | 3.55 |
| 325.77 | 4.32 | 4.32 |
| 360.84 | 4.68 | 4.68 |
| 296.15 | 4.36 | 4.36 |
| 241.29 | 3.75 | 3.75 |
| 372.55 | 3.81 | 3.81 |
| 239.31 | 1.31 | 1.31 |
| 303.83 | 4.19 | 4.19 |
| 276.21 | 3.21 | 3.21 |
| 381.69 | 5.80 | 5.80 |
| 319.25 | 3.93 | 3.93 |
| 404.49 | 3.80 | 3.80 |
| 477.05 | 5.09 | 5.09 |
| 1202.63 | ||
| 404.34 | 5.50 | 5.50 |
| 301.39 | 2.96 | 2.96 |
| 720.96 | 5.91 | 5.91 |
| 446.91 | 4.28 | 4.28 |
| 493.62 | 4.59 | 4.59 |
| 551.63 | 4.20 | 4.20 |
| 514.63 | 7.26 | 7.26 |
| 418.57 | 4.59 | 4.59 |
| 118.16 | -0.22 | -0.22 |
| 812.02 | 4.93 | 4.93 |
| 357.49 | 3.34 | 3.34 |
| 473.41 | 7.49 | 7.49 |
| 531.44 | 4.21 | 4.21 |
| 464.83 | 5.55 | 5.55 |
| 581.58 | -8.16 | -8.16 |
| 822.95 | 4.34 | 4.34 |
| 418.45 | 2.97 | 2.97 |
| 424.09 | 5.46 | 5.46 |
| 847.02 | 4.62 | 4.62 |
| 697.78 | 4.75 | 4.75 |
| 392.58 | 4.48 | 4.48 |
| 337.46 | 4.22 | 4.22 |
| 490.63 | 3.07 | 3.07 |
| 479.53 | 3.68 | 3.68 |
| 422.92 | 4.27 | 4.27 |
| 346.34 | 2.18 | 2.18 |
| 428.54 | 4.78 | 4.78 |
| 650.98 | 3.95 | 3.95 |
| 408.92 | 2.17 | 2.17 |
| 441.40 | -0.04 | -0.04 |
| 388.42 | 3.20 | 3.20 |
| 466.98 | 4.10 | 4.10 |
| 384.52 | 4.43 | 4.43 |
| 427.37 | 3.41 | 3.41 |
| 1056.40 | 2.75 | 2.75 |
| 411.47 | 4.63 | 4.63 |