Basic Information
ID: ALA4011817
Type: Binding
Description: Inhibition of recombinant human Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus expression system using FITC-labeled MCM2 peptide as substrate measured after 5 hrs in presence of 5 uM ATP
Format: BAO_0000019
Organism: Homo sapiens
Target: CDC7/DBF4 (Cell division cycle 7-related protein kinase/Activator of S phase kinase)(ALA2111377)
Document: ALA4011589
Inhibition of recombinant human Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus expression system using FITC-labeled MCM2 peptide as substrate measured after 5 hrs in presence of 5 uM ATP: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4011817
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.37 | 3.24 | 3.24 |
| 395.80 | 3.65 | 3.65 |
| 362.35 | 2.39 | 2.39 |
| 395.80 | 3.65 | 3.65 |
| 375.38 | 2.68 | 2.68 |
| 346.35 | 2.31 | 2.31 |
| 412.41 | 3.55 | 3.55 |
| 409.83 | 4.04 | 4.04 |
| 379.35 | 3.14 | 3.14 |
| 389.41 | 3.62 | 3.62 |
| 391.38 | 3.01 | 3.01 |
| 362.35 | 2.39 | 2.39 |
| 375.38 | 3.31 | 3.31 |
| 374.40 | 2.96 | 2.96 |
| 389.41 | 2.72 | 2.72 |
| 361.36 | 3.00 | 3.00 |
| 362.35 | 2.39 | 2.39 |
| 391.38 | 3.01 | 3.01 |
| 379.35 | 3.14 | 3.14 |
| 347.33 | 2.91 | 2.91 |
| 391.45 | 4.11 | 4.11 |
| 351.32 | 1.72 | 1.72 |
| 395.80 | 3.65 | 3.65 |
| 401.38 | 2.88 | 2.88 |
| 397.34 | 3.28 | 3.28 |
| 391.38 | 3.01 | 3.01 |
| 365.39 | 3.53 | 3.53 |
| 375.38 | 3.39 | 3.39 |
| 375.38 | 3.31 | 3.31 |
| 414.47 | 3.84 | 3.84 |
| 363.33 | 1.79 | 1.79 |