Assay Report Card

Basic Information

ID: ALA4012178

Type: Binding

Description: Ratio of IP for inhibition of HIV-1 integrase G140S/Q148H double mutant strand transfer activity to IP for inhibition of wild-type HIV-1 integrase strand transfer activity assessed as reduction in viral replication in presence of 10% normal human serum

Organism: Human immunodeficiency virus 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
443.862.372.37
501.942.462.46
487.922.082.08
515.973.123.12
501.942.462.46
568.992.232.23
509.922.942.94
493.923.243.24
617.033.383.38
531.972.092.09
431.852.522.52
443.862.372.37
473.933.643.64
591.062.122.12
457.893.073.07
493.923.243.24
540.982.362.36
515.973.123.12
479.902.942.94
504.912.812.81
584.001.981.98
544.023.903.90
501.942.732.73
493.923.243.24
579.051.971.97
515.972.852.85
510.912.342.34
542.013.513.51
445.882.762.76
493.923.243.24
606.081.581.58
431.852.472.47
571.001.941.94