Basic Information
ID: ALA4012237
Type: Binding
Description: Inhibition of human Nav1.7 expressed in HEK293 cells incubated for 3 to 5 mins at -125 mV holding potential by electrophysiology assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4012237
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 486.53 | 5.31 | 5.31 |
| 466.47 | 4.58 | 4.58 |
| 527.00 | 6.02 | 6.02 |
| 520.97 | 5.96 | 5.96 |
| 509.95 | 6.16 | 6.16 |
| 518.50 | 5.52 | 5.52 |
| 460.44 | 4.52 | 4.52 |
| 543.50 | 6.52 | 6.52 |
| 539.97 | 5.46 | 5.46 |
| 525.51 | 6.39 | 6.39 |
| 525.95 | 5.45 | 5.45 |
| 510.93 | 5.55 | 5.55 |
| 489.53 | 5.81 | 5.81 |
| 510.93 | 5.55 | 5.55 |
| 520.97 | 5.96 | 5.96 |
| 493.49 | 5.64 | 5.64 |
| 509.95 | 6.16 | 6.16 |
| 523.97 | 6.47 | 6.47 |
| 550.52 | 6.26 | 6.26 |
| 525.95 | 5.86 | 5.86 |
| 525.95 | 5.14 | 5.14 |
| 543.50 | 6.52 | 6.52 |
| 509.95 | 6.16 | 6.16 |
| 520.97 | 5.96 | 5.96 |
| 540.96 | 4.86 | 4.86 |
| 511.48 | 5.78 | 5.78 |
| 524.51 | 5.05 | 5.05 |