Basic Information
ID: ALA4012330
Type: ADME
Description: Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate in presence of NADPH
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4012330
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 540.96 | 4.95 | 4.95 |
| 559.50 | 5.61 | 5.61 |
| 509.49 | 4.73 | 4.73 |
| 559.50 | 5.61 | 5.61 |
| 557.51 | 5.20 | 5.20 |
| 505.53 | 4.90 | 4.90 |
| 525.95 | 5.25 | 5.25 |
| 527.48 | 4.87 | 4.87 |
| 539.97 | 5.56 | 5.56 |
| 523.52 | 5.04 | 5.04 |
| 533.01 | 5.22 | 5.22 |
| 567.00 | 5.06 | 5.06 |
| 551.00 | 5.36 | 5.36 |
| 527.48 | 4.87 | 4.87 |
| 525.95 | 5.25 | 5.25 |
| 555.53 | 5.78 | 5.78 |
| 541.51 | 5.47 | 5.47 |
| 551.00 | 5.36 | 5.36 |
| 555.53 | 5.78 | 5.78 |
| 523.52 | 5.04 | 5.04 |
| 533.01 | 5.22 | 5.22 |
| 554.96 | 5.19 | 5.19 |
| 559.50 | 5.61 | 5.61 |
| 552.53 | 5.28 | 5.28 |
| 543.94 | 5.39 | 5.39 |
| 471.48 | 4.50 | 4.50 |
| 510.48 | 4.13 | 4.13 |
| 509.49 | 4.73 | 4.73 |
| 519.55 | 5.21 | 5.21 |