Assay Report Card

Basic Information

ID: ALA4012370

Type: Functional

Description: Antipruritic activity in histamine-induced scratching C57BL/6 mouse model assessed as unbound plasma concentration required to show reduction in histamine-induced scratching bouts at 30 mg/kg, po administered 4 hrs prior to histamine challenge measured after 30 mins

Organism: Mus musculus

Strain: C57BL/6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
552.535.285.28