Basic Information
ID: ALA4012392
Type: Binding
Description: Inhibition of recombinant full-length human N-terminal GST tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using L-kynurenine as substrate measured after 2 hrs in presence of NADPH by RapidFire mass spectrometric method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4012392
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 204.01 | 2.84 | 2.84 |
| 190.20 | 1.51 | 1.51 |
| 224.65 | 2.16 | 2.16 |
| 404.85 | 2.85 | 2.85 |
| 271.66 | 1.73 | 1.73 |
| 241.63 | 1.72 | 1.72 |
| 225.63 | 1.56 | 1.56 |
| 304.73 | 2.08 | 2.08 |
| 223.66 | 2.77 | 2.77 |
| 304.73 | 2.08 | 2.08 |
| 239.66 | 1.10 | 1.10 |
| 238.67 | 2.55 | 2.55 |
| 266.64 | 1.59 | 1.59 |
| 238.67 | 2.41 | 2.41 |
| 238.67 | 2.47 | 2.47 |
| 406.82 | 2.12 | 2.12 |
| 269.10 | 2.27 | 2.27 |
| 430.76 | 2.74 | 2.74 |
| 240.65 | 1.14 | 1.14 |
| 238.67 | 2.73 | 2.73 |
| 420.85 | 2.51 | 2.51 |
| 237.21 | 1.08 | 1.08 |
| 204.23 | 1.82 | 1.82 |
| 346.77 | 2.50 | 2.50 |
| 390.82 | 2.29 | 2.29 |
| 224.65 | 2.16 | 2.16 |
| 224.65 | 2.16 | 2.16 |
| 240.65 | 1.46 | 1.46 |
| 275.18 | 2.09 | 2.09 |
| 210.62 | 1.77 | 1.77 |
| 418.83 | 2.26 | 2.26 |
| 255.66 | 1.54 | 1.54 |
| 232.19 | 0.94 | 0.94 |