Basic Information
ID: ALA4012419
Type: Binding
Description: Inhibition of human BRD4-BD1 (49 to 170 residues) expressed in Escherichia coli BL21(DE3) using N-C:SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGA-K(Ac)-RHRKVGG-K(biotin) as substrate preincubated for 15 mins followed by substrate addition measured after 5 mins by AlphaScreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4012419
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 418.50 | 3.18 | 3.18 |
| 508.58 | 5.48 | 5.48 |
| 316.36 | 1.77 | 1.77 |
| 333.41 | 2.79 | 2.79 |
| 400.39 | 1.80 | 1.80 |
| 404.22 | 2.60 | 2.60 |
| 247.25 | 1.50 | 1.50 |
| 318.40 | 2.51 | 2.51 |
| 379.42 | 3.78 | 3.78 |
| 370.43 | 1.88 | 1.88 |
| 321.36 | 0.84 | 0.84 |
| 269.30 | 2.49 | 2.49 |
| 366.42 | 3.38 | 3.38 |
| 309.76 | 2.06 | 2.06 |
| 359.39 | 3.18 | 3.18 |
| 377.49 | 3.41 | 3.41 |
| 329.44 | 5.46 | 5.46 |
| 309.32 | 3.00 | 3.00 |
| 323.35 | 2.42 | 2.42 |
| 308.35 | 1.50 | 1.50 |
| 315.25 | 2.17 | 2.17 |
| 298.30 | 2.23 | 2.23 |
| 411.68 | 4.10 | 4.10 |
| 354.38 | 3.51 | 3.51 |
| 330.41 | 2.60 | 2.60 |
| 313.74 | 2.51 | 2.51 |
| 396.92 | 4.96 | 4.96 |
| 342.42 | 3.43 | 3.43 |
| 356.41 | 1.53 | 1.53 |
| 366.44 | 3.93 | 3.93 |
| 335.23 | 4.92 | 4.92 |
| 326.35 | 2.96 | 2.96 |
| 316.41 | 1.42 | 1.42 |
| 313.36 | 1.86 | 1.86 |
| 288.35 | 1.93 | 1.93 |
| 304.37 | 2.12 | 2.12 |
| 372.45 | 2.92 | 2.92 |
| 385.81 | 2.84 | 2.84 |
| 338.43 | 4.36 | 4.36 |
| 314.37 | 2.70 | 2.70 |
| 443.94 | 4.30 | 4.30 |
| 313.32 | 4.70 | 4.70 |
| 416.23 | 3.39 | 3.39 |
| 342.79 | 2.16 | 2.16 |
| 356.45 | 3.81 | 3.81 |
| 303.41 | 2.14 | 2.14 |
| 370.84 | 4.02 | 4.02 |
| 391.23 | 2.17 | 2.17 |
| 416.30 | 4.48 | 4.48 |
| 316.40 | 3.10 | 3.10 |
| 342.36 | 0.39 | 0.39 |
| 322.62 | 3.68 | 3.68 |
| 333.34 | 1.84 | 1.84 |