Basic Information
ID: ALA4012481
Type: Binding
Description: Inhibition of human CYP11B2 expressed in HEK293A cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition measured after 1 hr by HTRF assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4012481
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 223.28 | 2.68 | 2.68 |
| 366.42 | 1.60 | 1.60 |
| 412.52 | 3.08 | 3.08 |
| 392.48 | 1.93 | 1.93 |
| 295.32 | 3.44 | 3.44 |
| 378.43 | 2.21 | 2.21 |
| 387.47 | 1.80 | 1.80 |
| 394.47 | 2.24 | 2.24 |
| 436.55 | 3.41 | 3.41 |
| 380.45 | 2.06 | 2.06 |
| 366.42 | 1.67 | 1.67 |
| 302.35 | 2.39 | 2.39 |
| 362.46 | 1.93 | 1.93 |
| 448.44 | 2.78 | 2.78 |
| 361.47 | 1.77 | 1.77 |
| 397.50 | 2.47 | 2.47 |
| 430.45 | 2.94 | 2.94 |
| 376.48 | 2.23 | 2.23 |
| 422.53 | 2.87 | 2.87 |
| 387.38 | 2.86 | 2.86 |
| 380.45 | 2.06 | 2.06 |
| 394.47 | 2.45 | 2.45 |
| 261.30 | 3.19 | 3.19 |