Basic Information
ID: ALA4012550
Type: Functional
Description: Inhibition of heat shock response in human INA-6 cells assessed as reduction in HSF-1 mediated upregulation of the heat shock protein HSP27 at 50 uM preincubated for 4 hrs followed by HSP90 inhibitor and HSR inducer NVP-AUY922 addition measured after 4 hrs by ELISA
Organism: Homo sapiens
Cell type: INA-6
Activity Charts
Bioactivity
Activity Types for Assay ALA4012550
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 517.46 | 5.07 | 5.07 |
| 477.83 | 5.66 | 5.66 |
| 631.40 | 5.99 | 5.99 |
| 618.78 | 3.33 | 3.33 |
| 552.50 | 5.23 | 5.23 |
| 936.03 | 6.05 | 6.05 |
| 428.53 | 4.37 | 4.37 |
| 410.52 | 4.75 | 4.75 |
| 513.48 | 5.90 | 5.90 |
| 535.48 | 5.44 | 5.44 |
| 829.08 | 4.51 | 4.51 |
| 491.43 | 5.43 | 5.43 |
| 845.08 | 4.22 | 4.22 |
| 507.43 | 5.14 | 5.14 |
| 463.38 | 4.98 | 4.98 |