Basic Information
ID: ALA4012824
Type: Binding
Description: Positive allosteric modulation of recombinant rat GluN1/GluN2C receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and glycine-induced current response at 30 uM at holding potential -40mV by two electrode voltage clamp method relative to control
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4012824
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 437.92 | 5.18 | 5.18 |
| 450.97 | 5.23 | 5.23 |
| 540.52 | 6.99 | 6.99 |
| 481.54 | 5.97 | 5.97 |
| 493.64 | 6.75 | 6.75 |
| 524.46 | 6.45 | 6.45 |
| 482.05 | 6.49 | 6.49 |
| 482.05 | 6.49 | 6.49 |
| 557.43 | 5.91 | 5.91 |
| 537.45 | 5.11 | 5.11 |
| 519.95 | 6.84 | 6.84 |
| 446.55 | 4.88 | 4.88 |
| 494.03 | 6.73 | 6.73 |
| 463.55 | 5.83 | 5.83 |
| 514.06 | 7.02 | 7.02 |
| 477.58 | 6.08 | 6.08 |
| 499.53 | 6.32 | 6.32 |
| 491.03 | 6.16 | 6.16 |
| 465.98 | 5.95 | 5.95 |
| 521.66 | 7.36 | 7.36 |
| 461.56 | 5.31 | 5.31 |
| 489.59 | 6.36 | 6.36 |
| 465.98 | 5.96 | 5.96 |
| 463.55 | 5.83 | 5.83 |
| 479.62 | 6.37 | 6.37 |
| 479.62 | 6.37 | 6.37 |
| 480.00 | 6.34 | 6.34 |
| 451.95 | 5.57 | 5.57 |
| 527.58 | 7.10 | 7.10 |
| 463.55 | 5.83 | 5.83 |
| 464.99 | 5.99 | 5.99 |
| 449.52 | 5.44 | 5.44 |
| 507.03 | 5.39 | 5.39 |
| 495.42 | 5.34 | 5.34 |
| 496.07 | 6.88 | 6.88 |
| 480.00 | 6.34 | 6.34 |
| 465.59 | 5.98 | 5.98 |
| 510.10 | 7.27 | 7.27 |
| 465.98 | 5.95 | 5.95 |
| 476.53 | 5.21 | 5.21 |
| 493.00 | 5.00 | 5.00 |
| 494.03 | 6.73 | 6.73 |
| 447.53 | 5.01 | 5.01 |
| 459.59 | 6.00 | 6.00 |
| 465.98 | 5.95 | 5.95 |
| 506.04 | 6.88 | 6.88 |
| 449.52 | 5.44 | 5.44 |
| 494.03 | 6.59 | 6.59 |
| 475.59 | 5.70 | 5.70 |
| 529.62 | 7.25 | 7.25 |
| 497.99 | 6.48 | 6.48 |
| 463.55 | 5.83 | 5.83 |
| 543.65 | 7.63 | 7.63 |
| 477.58 | 6.22 | 6.22 |
| 513.56 | 6.71 | 6.71 |
| 503.49 | 6.33 | 6.33 |
| 482.05 | 6.49 | 6.49 |
| 465.98 | 5.95 | 5.95 |
| 465.98 | 5.95 | 5.95 |
| 479.02 | 6.01 | 6.01 |
| 445.56 | 5.69 | 5.69 |