Basic Information
ID: ALA4012827
Type: Binding
Description: Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and glycine-induced current response at 10 uM at holding potential -40mV by two electrode voltage clamp method relative to control
Format: BAO_0000019
Organism: Rattus norvegicus
Target: Ionotropic glutamate receptor NMDA 1/2D(ALA3038506)
Document: ALA4011622
Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and glycine-induced current response at 10 uM at holding potential -40mV by two electrode voltage clamp method relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4012827
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 510.43 | 6.06 | 6.06 |
| 480.00 | 6.20 | 6.20 |
| 514.45 | 7.00 | 7.00 |
| 506.04 | 6.88 | 6.88 |
| 465.98 | 5.95 | 5.95 |
| 514.45 | 7.00 | 7.00 |
| 480.00 | 6.34 | 6.34 |