Basic Information
ID: ALA4012831
Type: Binding
Description: Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as compound concentration required to show two fold increase in glutamate and glycine-induced current response at holding potential -40mV by two electrode voltage clamp method
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4012831
CD
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 493.64 | 6.75 | 6.75 |
| 482.05 | 6.49 | 6.49 |
| 482.05 | 6.49 | 6.49 |
| 514.06 | 7.02 | 7.02 |
| 465.98 | 5.95 | 5.95 |
| 479.62 | 6.37 | 6.37 |
| 463.55 | 5.83 | 5.83 |
| 449.52 | 5.44 | 5.44 |
| 465.59 | 5.98 | 5.98 |
| 510.10 | 7.27 | 7.27 |
| 465.98 | 5.95 | 5.95 |