Basic Information
ID: ALA4012832
Type: Binding
Description: Positive allosteric modulation of recombinant rat GluN1/GluN2C receptor expressed in xenopus laevis oocyte assessed as compound concentration required to show two fold increase in glutamate and glycine-induced current response at holding potential -40mV by two electrode voltage clamp method
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4012832
CD
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 482.05 | 6.49 | 6.49 |
| 482.05 | 6.49 | 6.49 |
| 465.98 | 5.95 | 5.95 |
| 449.52 | 5.44 | 5.44 |
| 496.07 | 6.88 | 6.88 |
| 465.59 | 5.98 | 5.98 |
| 465.98 | 5.95 | 5.95 |
| 465.98 | 5.95 | 5.95 |
| 482.05 | 6.49 | 6.49 |