Positive allosteric modulation of recombinant rat GluN1/GluN2A receptor expressed in xenopus laevis oocyte co-expressing GluN2B assessed as potentiati...

Basic Information

ID: ALA4012834

Type: Binding

Description: Positive allosteric modulation of recombinant rat GluN1/GluN2A receptor expressed in xenopus laevis oocyte co-expressing GluN2B assessed as potentiation of glutamate and glycine-induced current response at 10 uM at holding potential -40mV by two electrode voltage clamp method relative to control

Format: BAO_0000019

Organism: Rattus norvegicus

Target:  Glutamate NMDA receptor; Grin1/Grin2a(ALA2096680)

Document:  ALA4011622

Positive allosteric modulation of recombinant rat GluN1/GluN2A receptor expressed in xenopus laevis oocyte co-expressing GluN2B assessed as potentiation of glutamate and glycine-induced current response at 10 uM at holding potential -40mV by two electrode voltage clamp method relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
463.555.835.83