Basic Information
ID: ALA4012835
Type: Binding
Description: Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte co-expressing GluN2A at 10 uM assessed as potentiation of glutamate and glycine-induced current response at holding potential -40mV by two electrode voltage clamp method relative to control
Format: BAO_0000019
Organism: Rattus norvegicus
Target: Glutamate NMDA receptor; Grin1/Grin2b(ALA2096666)
Document: ALA4011622
Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte co-expressing GluN2A at 10 uM assessed as potentiation of glutamate and glycine-induced current response at holding potential -40mV by two electrode voltage clamp method relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4012835
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 463.55 | 5.83 | 5.83 |