Positive allosteric modulation of recombinant rat GluN1/GluN2A/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamat...

Basic Information

ID: ALA4012836

Type: Binding

Description: Positive allosteric modulation of recombinant rat GluN1/GluN2A/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and glycine-induced current response at 10 uM at holding potential -40mV by two electrode voltage clamp method relative to control

Format: BAO_0000019

Organism: Rattus norvegicus

Target:  Ionotropic glutamate receptor NMDA1/2A/2B(ALA4106156)

Document:  ALA4011622

Positive allosteric modulation of recombinant rat GluN1/GluN2A/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and glycine-induced current response at 10 uM at holding potential -40mV by two electrode voltage clamp method relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
463.555.835.83