Assay Report Card

Basic Information

ID: ALA4012848

Type: Binding

Description: Activation of HRI in mouse KLN cells transfected with 5'UTR of ATF-4 mRNA fused firefly luciferase mRNA and 5'UTR lacking uORF fused renila luciferase mRNA assessed as increase in eIF2alpha phosphorylation by measuring ratio of firefly luciferase to renila luciferase at 1.25 uM after 16 hrs

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
462.396.126.12
446.396.246.24
360.423.943.94
505.425.215.21
360.423.943.94
491.396.146.14
403.405.095.09
519.446.076.07
403.405.095.09
447.385.635.63
462.396.126.12
456.347.047.04
478.396.006.00
489.425.335.33
489.425.335.33
428.414.964.96
503.446.196.19
505.425.215.21
440.347.167.16
471.406.116.11
403.405.095.09
471.406.116.11
514.397.257.25
428.414.964.96