Basic Information
ID: ALA4012848
Type: Binding
Description: Activation of HRI in mouse KLN cells transfected with 5'UTR of ATF-4 mRNA fused firefly luciferase mRNA and 5'UTR lacking uORF fused renila luciferase mRNA assessed as increase in eIF2alpha phosphorylation by measuring ratio of firefly luciferase to renila luciferase at 1.25 uM after 16 hrs
Format: BAO_0000219
Organism: Mus musculus
Target: Eukaryotic translation initiation factor 2-alpha kinase 1(ALA1938213)
Document: ALA4011623
Activation of HRI in mouse KLN cells transfected with 5'UTR of ATF-4 mRNA fused firefly luciferase mRNA and 5'UTR lacking uORF fused renila luciferase mRNA assessed as increase in eIF2alpha phosphorylation by measuring ratio of firefly luciferase to renila luciferase at 1.25 uM after 16 hrs: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4012848
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.39 | 6.12 | 6.12 |
| 446.39 | 6.24 | 6.24 |
| 360.42 | 3.94 | 3.94 |
| 505.42 | 5.21 | 5.21 |
| 360.42 | 3.94 | 3.94 |
| 491.39 | 6.14 | 6.14 |
| 403.40 | 5.09 | 5.09 |
| 519.44 | 6.07 | 6.07 |
| 403.40 | 5.09 | 5.09 |
| 447.38 | 5.63 | 5.63 |
| 462.39 | 6.12 | 6.12 |
| 456.34 | 7.04 | 7.04 |
| 478.39 | 6.00 | 6.00 |
| 489.42 | 5.33 | 5.33 |
| 489.42 | 5.33 | 5.33 |
| 428.41 | 4.96 | 4.96 |
| 503.44 | 6.19 | 6.19 |
| 505.42 | 5.21 | 5.21 |
| 440.34 | 7.16 | 7.16 |
| 471.40 | 6.11 | 6.11 |
| 403.40 | 5.09 | 5.09 |
| 471.40 | 6.11 | 6.11 |
| 514.39 | 7.25 | 7.25 |
| 428.41 | 4.96 | 4.96 |