Basic Information
ID: ALA4012849
Type: Binding
Description: Activation of HRI in mouse KLN cells transfected with 5'UTR of ATF-4 mRNA fused firefly luciferase mRNA and 5'UTR lacking uORF fused renila luciferase mRNA assessed as increase in eIF2alpha phosphorylation by measuring ratio of firefly luciferase to renila luciferase at 5 uM after 16 hrs
Format: BAO_0000219
Organism: Mus musculus
Target: Eukaryotic translation initiation factor 2-alpha kinase 1(ALA1938213)
Document: ALA4011623
Activation of HRI in mouse KLN cells transfected with 5'UTR of ATF-4 mRNA fused firefly luciferase mRNA and 5'UTR lacking uORF fused renila luciferase mRNA assessed as increase in eIF2alpha phosphorylation by measuring ratio of firefly luciferase to renila luciferase at 5 uM after 16 hrs: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4012849
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.39 | 6.12 | 6.12 |
| 446.39 | 6.24 | 6.24 |
| 360.42 | 3.94 | 3.94 |
| 505.42 | 5.21 | 5.21 |
| 360.42 | 3.94 | 3.94 |
| 491.39 | 6.14 | 6.14 |
| 403.40 | 5.09 | 5.09 |
| 519.44 | 6.07 | 6.07 |
| 403.40 | 5.09 | 5.09 |
| 447.38 | 5.63 | 5.63 |
| 462.39 | 6.12 | 6.12 |
| 456.34 | 7.04 | 7.04 |
| 478.39 | 6.00 | 6.00 |
| 489.42 | 5.33 | 5.33 |
| 489.42 | 5.33 | 5.33 |
| 428.41 | 4.96 | 4.96 |
| 503.44 | 6.19 | 6.19 |
| 505.42 | 5.21 | 5.21 |
| 440.34 | 7.16 | 7.16 |
| 471.40 | 6.11 | 6.11 |
| 403.40 | 5.09 | 5.09 |
| 471.40 | 6.11 | 6.11 |
| 514.39 | 7.25 | 7.25 |
| 428.41 | 4.96 | 4.96 |