Basic Information
ID: ALA4012895
Type: Binding
Description: Inhibition of TNKS1 (unknown origin) expressed in HEK293 cells co-expressing TCF/LEF luciferase plasmid assessed as reduction in wnt3a ligand-induced Wnt-dependent increase in beta-catenin preincubated for 1 hr followed by wnt3a ligand stimulation for 24 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4012895
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 296.72 | 3.07 | 3.07 |
| 276.30 | 2.72 | 2.72 |
| 262.28 | 2.42 | 2.42 |
| 305.35 | 2.48 | 2.48 |
| 276.30 | 2.72 | 2.72 |
| 482.51 | 1.75 | 1.75 |
| 304.36 | 3.54 | 3.54 |
| 306.29 | 2.11 | 2.11 |
| 486.54 | 2.13 | 2.13 |
| 377.41 | 2.13 | 2.13 |
| 363.38 | 1.79 | 1.79 |
| 468.48 | 1.74 | 1.74 |
| 458.53 | 2.35 | 2.35 |
| 319.33 | 2.37 | 2.37 |
| 373.42 | 3.04 | 3.04 |
| 374.41 | 1.46 | 1.46 |
| 287.29 | 2.29 | 2.29 |
| 480.49 | 1.80 | 1.80 |
| 451.49 | 2.77 | 2.77 |
| 375.39 | 1.89 | 1.89 |
| 451.49 | 2.77 | 2.77 |
| 345.37 | 2.54 | 2.54 |
| 280.27 | 2.56 | 2.56 |
| 452.48 | 2.17 | 2.17 |
| 375.39 | 1.89 | 1.89 |
| 482.51 | 1.75 | 1.75 |
| 361.37 | 1.78 | 1.78 |
| 304.36 | 3.54 | 3.54 |
| 468.48 | 1.74 | 1.74 |
| 393.38 | 2.03 | 2.03 |
| 482.51 | 1.75 | 1.75 |
| 442.48 | 2.11 | 2.11 |
| 416.45 | 1.72 | 1.72 |
| 452.48 | 2.17 | 2.17 |
| 333.36 | 2.40 | 2.40 |
| 451.49 | 2.77 | 2.77 |
| 276.30 | 2.72 | 2.72 |