Basic Information
ID: ALA4013170
Type: Binding
Description: Inhibition of recombinant human His-tagged GAB (P56 to V602 residues) expressed in Escherichia coli C41(DE3)pLysS using glutamine as substrate preincubated for 10 mins followed by substrate addition measured after 60 mins by glutamate dehydrogenase coupled enzyme assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Glutaminase liver isoform, mitochondrial(ALA4105730)
Document: ALA4011632
Inhibition of recombinant human His-tagged GAB (P56 to V602 residues) expressed in Escherichia coli C41(DE3)pLysS using glutamine as substrate preincubated for 10 mins followed by substrate addition measured after 60 mins by glutamate dehydrogenase coupled enzyme assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4013170
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 655.76 | 8.13 | 8.13 |
| 554.65 | 5.84 | 5.84 |
| 559.67 | 5.98 | 5.98 |
| 531.62 | 5.42 | 5.42 |
| 377.26 | 4.18 | 4.18 |
| 529.64 | 5.97 | 5.97 |
| 501.41 | 6.90 | 6.90 |
| 536.03 | 6.06 | 6.06 |
| 637.79 | 8.25 | 8.25 |
| 667.82 | 8.26 | 8.26 |
| 517.59 | 5.11 | 5.11 |
| 653.79 | 8.69 | 8.69 |
| 625.73 | 8.13 | 8.13 |
| 501.59 | 5.41 | 5.41 |
| 665.84 | 8.81 | 8.81 |
| 513.46 | 7.02 | 7.02 |