Basic Information
ID: ALA4013283
Type: Functional
Description: Antiarthritic activity in MIA-induced osteoarthritis Lewis rat model assessed as decrease in aggrecan degradation products by measuring ARGNV levels in synovial fluid at 30 mg/kg, po bid starting on day 3 post MIA induction measured at 4 hrs post single oral dose on day 7 by ELISA relative to control
Format: BAO_0000218
Organism: Rattus norvegicus
Strain: Lewis
Target: Rattus norvegicus(ALA376)
Document: ALA4011634
Antiarthritic activity in MIA-induced osteoarthritis Lewis rat model assessed as decrease in aggrecan degradation products by measuring ARGNV levels in synovial fluid at 30 mg/kg, po bid starting on day 3 post MIA induction measured at 4 hrs post single oral dose on day 7 by ELISA relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4013283
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 472.92 | 2.47 | 2.47 |
| 409.41 | 2.38 | 2.38 |