Antiarthritic activity in MIA-induced osteoarthritis Lewis rat model assessed as decrease in aggrecan degradation products by measuring ARGNV levels i...

Basic Information

ID: ALA4013284

Type: Functional

Description: Antiarthritic activity in MIA-induced osteoarthritis Lewis rat model assessed as decrease in aggrecan degradation products by measuring ARGNV levels in synovial fluid at 75 mg/kg, po bid starting on day 3 post MIA induction measured at 4 hrs post single oral dose on day 7 by ELISA relative to control

Format: BAO_0000218

Organism: Rattus norvegicus

Strain: Lewis

Target:  Rattus norvegicus(ALA376)

Document:  ALA4011634

Antiarthritic activity in MIA-induced osteoarthritis Lewis rat model assessed as decrease in aggrecan degradation products by measuring ARGNV levels in synovial fluid at 75 mg/kg, po bid starting on day 3 post MIA induction measured at 4 hrs post single oral dose on day 7 by ELISA relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
409.412.382.38