Basic Information
ID: ALA4013288
Type: Binding
Description: Inhibition of recombinant human complement factor D catalytic domain using Z-Lys-thiobenzylester as substrate preincubated for 1 hr followed by substrate addition by 2,4-dinitrobenzenesulfonyl-2,7-desmethyl-fluorecein probe based spectrofluorimetric assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Complement factor D(ALA2176771)
Document: ALA4011635
Inhibition of recombinant human complement factor D catalytic domain using Z-Lys-thiobenzylester as substrate preincubated for 1 hr followed by substrate addition by 2,4-dinitrobenzenesulfonyl-2,7-desmethyl-fluorecein probe based spectrofluorimetric assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4013288
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 489.45 | 4.35 | 4.35 |
| 475.43 | 4.10 | 4.10 |
| 489.45 | 4.35 | 4.35 |
| 489.45 | 4.49 | 4.49 |
| 493.42 | 4.05 | 4.05 |
| 493.42 | 4.05 | 4.05 |
| 491.43 | 3.07 | 3.07 |
| 511.41 | 4.35 | 4.35 |
| 490.44 | 3.04 | 3.04 |
| 500.33 | 2.66 | 2.66 |
| 482.34 | 2.53 | 2.53 |
| 483.33 | 3.36 | 3.36 |
| 483.33 | 1.92 | 1.92 |
| 475.43 | 4.10 | 4.10 |
| 482.34 | 3.96 | 3.96 |
| 487.44 | 4.10 | 4.10 |
| 487.44 | 3.96 | 3.96 |
| 489.43 | 4.36 | 4.36 |
| 433.47 | 3.21 | 3.21 |
| 469.45 | 3.80 | 3.80 |
| 504.44 | 3.78 | 3.78 |
| 482.34 | 3.02 | 3.02 |
| 505.43 | 4.24 | 4.24 |
| 437.89 | 3.85 | 3.85 |
| 472.43 | 3.62 | 3.62 |