Basic Information
ID: ALA4013311
Type: Binding
Description: Inhibition of complement factor D in human whole blood assessed as decrease in zymosan-induced AP activation mediated soluble MAC complex formation preincubated for 15 mins followed by zymosan addition measured after 40 mins by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4013311
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 500.33 | 2.66 | 2.66 |
| 482.34 | 2.53 | 2.53 |
| 483.33 | 3.36 | 3.36 |
| 483.33 | 1.92 | 1.92 |
| 482.34 | 3.96 | 3.96 |
| 487.44 | 4.10 | 4.10 |
| 489.43 | 4.36 | 4.36 |
| 433.47 | 3.21 | 3.21 |
| 469.45 | 3.80 | 3.80 |
| 504.44 | 3.78 | 3.78 |
| 482.34 | 3.02 | 3.02 |
| 505.43 | 4.24 | 4.24 |
| 437.89 | 3.85 | 3.85 |
| 472.43 | 3.62 | 3.62 |