Basic Information
ID: ALA4013437
Type: ADME
Description: Drug metabolism in human HuH7 cells assessed as carboxylesterase-mediated (S)-isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryloxy)propanoate metabolite formation at 50 uM after 48 hrs by LC/MS/MS analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4013437
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 598.56 | 3.10 | 3.10 |