Assay Report Card

Basic Information

ID: ALA4013447

Type: ADME

Description: Drug metabolism in human HuH7 cells assessed as carboxylesterase 1-mediated (S)-2-((R)-(((2R,3R,4R,5R)-5-(4-butyramido-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(hydroxy)phosphorylamino)propanoic acid metabolite formation at 50 uM after 24 hrs by LC/MS/MS analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
598.563.103.10