Basic Information
ID: ALA4013478
Type: Binding
Description: Inhibition of AcrA efflux pump in Escherichia coli BW25113 assessed as compound concentration required for potentiation of novobiocin-induced antibacterial activity by 4 fold by checkerboard assay
Format: BAO_0000019
Organism: Escherichia coli BW25113
Target: Unchecked(ALA612545)
Document: ALA4011640
Inhibition of AcrA efflux pump in Escherichia coli BW25113 assessed as compound concentration required for potentiation of novobiocin-induced antibacterial activity by 4 fold by checkerboard assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4013478
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 452.52 | 2.89 | 2.89 |
| 452.52 | 2.89 | 2.89 |
| 452.52 | 2.89 | 2.89 |
| 486.96 | 3.54 | 3.54 |
| 497.52 | 2.80 | 2.80 |
| 452.52 | 2.89 | 2.89 |
| 333.44 | 3.81 | 3.81 |
| 293.37 | 2.61 | 2.61 |
| 291.35 | 2.69 | 2.69 |
| 325.80 | 3.34 | 3.34 |
| 313.79 | 2.87 | 2.87 |
| 466.55 | 3.20 | 3.20 |
| 410.86 | 3.83 | 3.83 |
| 370.25 | 3.45 | 3.45 |
| 323.35 | 2.08 | 2.08 |
| 370.25 | 3.45 | 3.45 |
| 486.96 | 3.31 | 3.31 |
| 404.47 | 1.74 | 1.74 |
| 400.83 | 4.59 | 4.59 |
| 512.96 | 4.44 | 4.44 |
| 470.51 | 3.03 | 3.03 |
| 410.48 | 3.44 | 3.44 |
| 476.49 | 2.68 | 2.68 |
| 325.80 | 3.34 | 3.34 |
| 394.27 | 4.20 | 4.20 |
| 321.38 | 2.70 | 2.70 |
| 458.57 | 2.77 | 2.77 |
| 359.35 | 3.71 | 3.71 |
| 398.47 | 3.22 | 3.22 |
| 400.83 | 4.59 | 4.59 |
| 482.93 | 5.62 | 5.62 |
| 325.80 | 3.34 | 3.34 |
| 299.76 | 2.94 | 2.94 |
| 531.41 | 3.65 | 3.65 |
| 374.44 | 3.11 | 3.11 |