Basic Information
ID: ALA4013546
Type: Binding
Description: Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in HEK293F cells using histone H4 as substrate in presence of [3H]-SAM after 60 mins by chemiluminescent assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4013546
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.32 | 4.75 | 4.75 |
| 323.38 | 3.14 | 3.14 |
| 341.39 | 3.08 | 3.08 |
| 325.38 | 3.64 | 3.64 |